List of Best Python GUI Framework in 2021

Graphical User Interface is basically attaching visual objects to software to ease the user’s experience. These objects include icons, buttons, cursors, widgets and with the latest development in the field, we have started to see them being used with sounds and other visual effects like tabs and windows.

The purpose, as mentioned before, is to enhance user experience which was a big disadvantage with the previous CLI or Command-line interfaces.

GUI has now become the norm for software design and programming. It allows both developers and users to operate their systems with the use of graphical objects like the mouse cursor and the different icons we have for the apps we use.

Top 10 Python GUI Framework

PyQT (Qt cross-platform C++ framework)

PyQt:  cross-platform C++ framework

PyQt is built on the Qt framework. The Qt framework itself is a framework that works across multiple platforms and is known to be used for many applications.

PyQt is completely cross-platform and it allows applications to be made on Windows, iOS, Android, Mac, etc.

Why we think PyQt is so useful is because it offers a personalized GUI and a Designer module to accompany it. The module itself has a very user-friendly system and also gives the developer the freedom to create their own elements.

This makes it perfect for developers and also allows them to develop applications of all scales with comfort.

Kivy (Cross-platform Python Framework for NUI Development)

Kivy: Python Cross-platform Framework

Now Kivy is unique because it is written in both Python and Cython. It is licensed by MIT and is the most available 3D graphics API and its open source.

Kivy has one of the best GUI libraries for Python and Kivy also has a great graphics engine. Kivy allows the developer to code on one platform and uses it across multiple platforms.

The framework is manufactured in a manner making it compatible with game development as well. Kivy is most abundantly used in iOS and Android applications.

Tkinter (Python interface to Tcl/Tk)

Tkinter: Python interface to Tcl/Tk

Tkinter is probably the first framework a python developer thinks about. Tkinter’s aim was to give the developer a basic interface. It gives the developers visual objects that they term as ‘widgets.’

The widgets come with a range of customizing options. It is the most commonly used GUI framework and this is also because Tkinter comes as a part of Pythons standard library.

This means that this is always going to be convenient and standardized for development. Tkinter provides visual elements such as buttons, labels, frames, etc.

PySlide (Python Slide Image Analysis Toolkit)

PySlide: Python Slide Image Analysis Toolkit

PySide is similar to PyQt as it is a Python binding for Qt. This is particularly appealing because it allows you to run your Graphical User Interface on various platforms without having to alter your source code a lot.

PyQt and PySide are essentially the same but PySide is open source which means it allows the user to do more as they wish.

Anything that requires more customization and a more personalized approach then you should prefer using PySide.

Another plus side to PySide is the community support that it offers and a dedicated section for guides and other resources to help the developer.

WxPython (Cross-Platform GUI toolkit for Python)

WxPython: Cross-Platform GUI Python toolkit

It is a Python extension module and allows the user to create very functional Graphical User Interfaces. What most developers like about WxPython is its ease of use.

WxPython is open source as well and its source code is available to alter as needed by the developer and allows them to develop to improve the source code where needed.

It also allows developers to create native user interfaces to boost their applications.

Libavg GUI (GUI framework written in C++ and OpenGL)

Libavg: Python framework written in C++ and OpenGL

Libavg uses OpenGL and is used to make hardware acceleration. This is why most of its properties allow it to be a Python variable.

Like some of the previous frameworks, Libavg is an open-source Graphical User Interface and it also supports multiple platforms like Linux, Windows, and Mac.

It is very graphic intensive and hence supports video decoding, visual effects, etc. Furthermore, Libavg ensures great speed and it is known to enhance applications’ performance.

Another feature is the customization it offers with scaling, rotation, etc. for visual elements.

PyGUI (Python Framework for cross-platform pythonic GUI API)

PyGUI: Python Framework for cross-platform pythonic GUI API

PyGUI is another cross-platform GUI framework. It is known for its relative simplicity and developers can make user interfaces with native elements.

It is also lightweight so it does not burden the manufacturing of a program, supported by Windows and Mac OS.

It was made purely for Python and because it’s simple, it is a good starting point for someone new in the field. The API is perfectly synonymous with Python.

PySimpleGUI (easy Python GUI Framework)

PySimpleGUI: easy Python GUI Framework

PySimpleGUI is quite simply what its name states. It is normally the first framework a developer will probably learn to use as it is simple.

GUI frameworks are seen as difficult or terrifying, to begin with so PySimple is an easy way to begin. Its library is based on Tkinter.

It reduces the coding and makes everything look easy and condensed which is why it does not intimidate many developers with lengths of code.

PySimple doesn’t only appeal to the beginner however as it still has the option for full native functionality which the more expert developers would love to hear.

Wax GUI Toolkit (Easy Python GUI Framework)

Wax is like WxPython but not as complicated and slightly more user-friendly. It does work with different platforms as well; in case you were wondering.

Wax is similar to PySimple in the manner that it is made to bring ease to the developer

and provide a more simplistic approach. It removes the low-level parts from WxPython but maintains the speed and effectiveness of WxPython.

PyForms GUI

Pyforms: Python GUI framework

Pyforms is relatively newer in comparison to the other frameworks here. It has minimal coding and is renowned for Windows Forms.

This allows developers to create stunning user interfaces. It is cross-platform and allows developers to work across multiple platforms without changing the code too much.

Pyforms provides many libraries like PyQt and OpenGL as well, to assist the developer.

What is GUI Framework

A GUI framework basically incorporates existing elements of the operating system like windows, fonts, etc., and then condensing the elements to create a framework that works on many platforms, has a clean setup for classes and structures, and gives you the freedom to work around with it. It is for those who want a more personalized experience.

How does GUI works?

GUI consists of using a cursor and icons to navigate through the software. The user will click on the different icons to start a program or action. What GUI does is attach an image to a command line which is executed as the icon is clicked.

What are Python GUI Framework

Python has easily become one of the most popular programming languages in today’s world. We do not need to display stats to prove how renowned python has become.

Its popularity has come about possibly because of its ease of use and versatility. It is used for web development, game development, software development, and of course for GUI.

These python GUI frameworks come in handy in so many different places, like in the making of different software and animation, to name a few.

Creating a python-based user interface for your application makes it a lot more engaging. To build a GUI however, you will need a toolkit or framework to assist you with the creation of the interface.

This is absolutely detrimental as it forms the base for your applications, websites, etc. We hope you now realize the importance of Python GUI frameworks, now let’s get onto the best python GUI frameworks and why they are so efficient.


Now, these are our favorite Python GUI frameworks to use. For any application to work smoothly, the right usage of these frameworks is very important.

The frameworks mentioned each has their unique offerings and features. As you can see, there are multiple frameworks for Python GUI and they are all available to you.

Some of them are open-sourced and some of them are licensed, some work across all platforms, and some are limited to a few. Each however was made for the purpose of easing the Graphical User Interface making process.

Each framework has its own unique attributes and specialties. Every developer has their own preference. We recommend you give each one of these a go and see which one you like and which one helps you make the program or application you set out for. Good luck and we hope to hear your success stories.

Also read:

1 thought on “List of Best Python GUI Framework in 2021”

Comments are closed.

Scroll to Top